WHAT ARE ISOXAZOLINES?
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Research on Isoxazolines
Current research supports ISO-1's as MIF inhibitors.
Related research proposes a four-step process as an ideal way of synthesizing isoxazolines:
1. Grignard reaction of p-anisaldehyde to form an alcohol with the functional group 3-buten-1-ol.
2. Oxidation of alcohol to make a ketone with the functional group 3-buten-1-one.
3. Treatment of the ketone with a hydroxylamine to yield a form of oxime.
4. Final cyclization of the oxime with a metalloid to synthesize a form of isoxazoline.
Related research proposes a four-step process as an ideal way of synthesizing isoxazolines:
1. Grignard reaction of p-anisaldehyde to form an alcohol with the functional group 3-buten-1-ol.
2. Oxidation of alcohol to make a ketone with the functional group 3-buten-1-one.
3. Treatment of the ketone with a hydroxylamine to yield a form of oxime.
4. Final cyclization of the oxime with a metalloid to synthesize a form of isoxazoline.
Questions to Answer:
- Can isoxazolines be produced en masse?
- How expensive would it be to produce isoxazolines on a large scale?
- Could the average person be able to purchase the drug?
- Could the average person be able to purchase the drug?
- Are the yields for the reactions high so that the drug could be commercialized?