- With the conditions used in this experimentation, the isoxazolines could not be produced en masse.
- Reactions take too much time.
- Yields are not high enough.
- However, these drugs are fairly inexpensive to make.
- The copper oxidizes the metalloids so that very little amounts are needed to form a product.
- Also, because they are relatively inexpensive to make, the price would be lowered, allowing every-day people to purchase the isoxazolines.